Entertainer's Secret is formulated to resemble natural secretions. Sodium carboxymethylcellulose, aloe vera gel, and glycerin – each a proxy for a naturally secreted type of mucus (globular, strand and sheet) – are blended into a buffered (via dibasic sodium phosphate), aqueous hypertonic (via potassium chloride) solution that is preserved with methyl and propyl parabens. Each ingredient has a very high safety profile.

Unlike some other sore throat remedies, it does NOT contain numbing anesthetics, alcohol, antiseptics, analgesics, antihistamines, decongestants, anti-inflammatory agents, or any other "medicinal" ingredient that can produce unwanted side effects. The improved honey-apple flavor imparts a pleasant mellow taste.